What is CBDVA?

What is cbdva

What is CBDVA

Most seasoned hemp enthusiasts fancy themselves as cannabinoid connoisseurs who have tried it all: CBD, CBG, CBDA, CBDV, delta 8 THC, and other cannabinoids found in the hemp plant that each offer valuable properties to the body through interaction with the endocannabinoid system. But, if there is one cannabinoid you likely haven’t heard of until now, it’s cannabidivarinic acid (CBDVA). Besides having more letters in its acronym than any other cannabinoid thus far, it’s proving to be quite a fascinating compound in terms of its capabilities. 

An Inside Look into CBDVA 

Most of what we are familiar with when it comes to cannabinoids are decarboxylated cannabinoids, which are naturally occurring cannabinoids that have been heated in a controlled manner to activate specific properties that change the way in which they absorb into and function in the body. Think about the raw hemp flower buds, and how we smoke them by applying fire to them. Simply eating the raw buds would not provide you with certain effects associated with decarboxylated cannabinoids like CBD, but would introduce different cannabinoids into the body, cannabidivarinic acid included.

When cannabinoids are decarboxylated, they bind directly to cannabinoid receptors throughout the bodily systems to produce regulatory actions that pertain to how bodily processes function. This is the key role of the body’s endocannabinoid system, which utilizes cannabinoids to keep the body in homeostasis.

Raw cannabinoids like CBDVA work a bit differently. They don’t seem to directly attach to cannabinoid receptors, but they do seem to play a regulatory role nonetheless through offering properties to bodily systems that improve overall functionality. These raw cannabinoids have been researched far less than decarboxylated ones, which is why we’re still only just learning about how they differ in terms of effects.

Cannabidivarinic acid is a precursor to cannabidivarin (CBDV), a cannabinoid in hemp that shares a lot in common with CBD due to impressive similarities in molecular structure. Any cannabinoid with an “A” at the end of its acronym implies that it’s a raw cannabinoid, as raw cannabinoids are acidic in nature before they are converted into their final form once decarboxylated. 

Raw cannabinoids like CBDVA are what you’ll find in the hemp plant in its natural state, before it has had heat applied to it in order to decarboxylate its compounds and change the way in which they work with the human body.

In more formal terms, CBDVA is a varin carboxylic acid, which means that its carbon side chain is shorter than other carboxylic acids like CBDA and CBGA. What this means in terms of how it interacts with the human body is that it works as a homolog of CBDA, meaning its chemical structure is similar enough to offer many of the same properties but with enough structural differences to be valuable independently.

Cannabidivarinic acid was, in fact, discovered in 1977 by a team of cannabis researchers in Japan, along with cannabigerovarinic acid (CBGVA), tetrahydrocannabivarin (THCVA), and cannabichromevarinic acid (CBCVA), all varin carboxylic acids found in cannabis. While the discovery is responsible for our modern understanding of the valuable nature of CBDVA, at the time, researchers disregarded any potential benefits of these types of compounds and so no research was done into their properties.

It wasn’t until 1988 when researchers began to take the potential of this cannabinoid more seriously. From there, CBDVA has been studied by numerous researchers, to paint a more accurate and richer picture of what it can offer to the human body.

What are the Properties of CBDVA?

The first study done on cannabidivarinic acid in 1988 showed that it has strong potential to offer anticonvulsant properties, which could be extremely useful to those who experience seizures. For the time-being, no other properties have been explored as researchers are focusing solely on its potential antiseizure activity. This does not mean that CBDVA will not be shown to offer numerous other properties, as we’ve seen in research done on all cannabinoids known at this time, including other acidic forms of cannabinoids like CBDA.

How to Take CBDVA 

Currently, CBDVA is not available on the market. It’s present in trace levels in the raw hemp plant, which has not been decarboxylated to convert CBDVA to CBDV. Researchers have managed to recreate cannabidivarinic acid using various methods that take advantage of the homolog relationship between CBDVA and CBDA, but these are not available in formulas that you can purchase on the market. 

We do not recommend attempting to produce cannabidivarinic acid at home, due to the highly unstable nature of the chemical compound paired with the advanced chemistry techniques needed. However, as more interest grows in CBDVA, you may find it pop up on the market sooner than later.

CBDVA: A Raw Cannabinoid with a Lot of Promise

This new generation of hemp derivatives is proving that the plant’s hundreds of individual compounds all offer fascinating value to the human body. As cannabidivarinic acid research continues, we’ll better understand what it’s capable of, and this will hopefully lead to CBDVA products that are available for purchase.

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